Course Description
Integration of cell biology and protein metabolism in relation to gene expression and regulation of enzyme activity in mammalian cells. Critical analysis of recent literature. Prerequisite: Previous course in general nutrition, biochemistry and mammalian physiology and unconditional admission to the graduate program in Nutrition or other life sciences, or permission of instructor.
Syllabus
Student Learning Outcomes, Goals, Objectives:
Students successfully completing this course will be able to:
- Demonstrate an understanding of the gene expression process and its regulation
- Discuss how nutrients contribute to gene transcription and identify nutritionally derived transcription factors.
- Identify how nutrition impacts epigenetics and how microRNA species influence gene transcription and translation in nutrition-related disorders.
- Demonstrate knowledge of cellular protein metabolism
- Discuss how amino acid availability and transport dictate how tissues metabolize protein.
- Identify mechanisms that regulate protein turnover and function.
- Critically evaluate how gene expression and protein metabolism affect health and disease
- Identify research methodology used to evaluate gene and protein function
Course Grading Information:
| Activity/Performance Measure | Percentage/Points |
|---|---|
| Exams (2 exams x 100 points) | 200 points |
| Presentations (2 presentations x 25 points) | 50 points |
| Engagement & Attendance | 50 points |
Grading Scale
| Percentage | Letter Grade |
|---|---|
| 93-100% | A |
| 90-92% | A- |
| 87-89% | B+ |
| 83-86% | B |
| 80-82% | B- |
| 77-79% | C+ |
| 73-76% | C |
| 70-72% | C- |
| 67-69% | D+ |
| 60-66% | D |
| 0-59% | F |
Attendance/Participation:
Attendance is required and graded.
Course Materials Purchased by the Students:
No course materials are required.
Scholarly Perspectives
This course engages diverse scholarly perspectives to develop critical thinking, analysis, and debate and inclusion of a reading does not imply endorsement.