Course Description
Current research activities in the analytical area, primarily for first year graduate students. Four areas emphasized: chemical equilibrium, spectroscopy, separations, and electrochemistry. Prerequisite: CHE 462 or CHE 406 or equivalent, one semester of instrumental analysis (CHE 703) recommended.
Syllabus
Student Learning Outcomes, Goals, Objectives:
Students successfully completing this course will be able to:
Understand the mechanism of various ionization techniques and predict the ionizability of biomolecules
Understand the working principles of various modern mass analyzers and be able to select suitable mass spectrometry methods for the analytical objective
Be able to interpret the high-resolution mass spectrum for the isotopic composition analysis and to analyze tandem mass spectrum for structural elucidation of biomolecules
Understand the principles of chromatographic separation and be able to develop suitable chromatographic methods for the analytical objective
Understand the quantitative aspects of mass spectrometry and the hyphenated mass spectrometric techniques
Understand the basics of proteomics, lipidomics and metabolomics
Course Grading Information:
Activity/Performance Measure | Percentage/Points |
|---|---|
10 Homework and quiz assignments | 20% |
3 Exams | 60% |
1 Term paper | 20% |
Grading Scale
Percentage | Letter Grade |
|---|---|
>=90% | A |
85-89% | A- |
80-84% | B+ |
75-79% | B |
70-74% | B- |
65-69% | C+ |
60-64% | C |
<60% | F |
Attendance/Participation:
Attendance will not be taken for the course but there is no make-up quiz.
Course Materials Purchased by the Students:
Mass Spectrometry: A Textbook, 3rd Edition, by Jurgen H. Gross, Publisher: Springer
Scholarly Perspectives
This course engages diverse scholarly perspectives to develop critical thinking, analysis, and debate and inclusion of a reading does not imply endorsement.