Unraveling the 3D Genome

Course Description

Exploration of emerging models of 3D organization of the genome. Emphasis placed on recent primary literature explored in supportive introduction to a journal club format. Universal design of learning will be embraced through means-ends analysis, learning probes, and think-pair-share activities. Prerequisite: BIO 355, BIO 375, BIO 392.

Syllabus

Student Learning Outcomes, Goals, Objectives:

Students successfully completing this course will be able to:

  • Identify the levels of genome organization.
  • Describe the main techniques used to investigate the 3D genome.
  • Explain the significant findings from recent literature on the 3D genome.
  • Articulate the main questions and findings of a primary journal article.
  • Contrast the techniques used to investigating chromatin structure.
  • Evaluate and critique authors’ claims with respect to presented data.
  • Design and present a journal club style presentation of a primary source.

Course Grading Information:

Activity/Performance Measure Percentage/Points
Journal Club 1 15%
Journal Club 2 20%
Worksheets 15%
Participation 10%
“What is a TAD?” 5%
Mini Exam 5%
Midterm 15%
Final 15%

Grading scale

Percentage Letter Grade
93-100%A
90-92%A-
87-89%B+
83-86%B
80-82%B-
77-79%C+
73-76%C
70-72%C-
67-69%D+
65-66%D
62-65%D-
< 62%F

Attendance/Participation:

In order to benefit from a discussion-based course, you must be there to discuss. If you are not in class, you will not receive points for the Participation points for that day. You are allowed to miss one class with no penalty.

Course Materials Purchased by the Students:

Physical iClicker2 Student Remote

Scholarly Perspectives

This course engages diverse scholarly perspectives to develop critical thinking, analysis, and debate and inclusion of a reading does not imply endorsement.